Elution of Monomers From CAD-CAM Materials and Conventional Resin Composite in Distilled Water and Artificial Saliva
The purpose of this study was to evaluate the leaching pattern of different types of polymer computer-aided design and computer-aided manufacturing (CAD-CAM) materials with a conventional resin composite. Specimens of three representatives by type of polymer CAD-CAM blocks and one conventional resin composite were suspended using a silk thread in distilled water and artificial saliva. After one day, seven days, 14 days, 30 days, and 60 days, the analysis of the eluates for the detection of bisphenol A (BPA), urethane dimethacrylate (UDMA), triethylene glycol dimethacrylate (TEGDMA) and bisphenol A-glycidyl dimethacrylate (Bis-GMA) was quantified by utilizing high-performance liquid chromatography (HPLC). TEGDMA was the main eluted monomer for the polymer CAD-CAM materials for both solutions. However, there was a decreasing pattern throughout the tested period. On the contrary, there was a constant release of monomers from the conventional resin composite. Bisphenol-A was released only by the conventional resin composite and in both solutions chosen. Different types of polymer CAD-CAM materials release minimal or no monomers compared to the conventional resin composite material. The methods of fabrication of polymer CAD-CAM materials produces better properties than the conventional resin composite with a dramatic decrease of monomer elution.SUMMARY
Purpose
Methods and Materials
Results
Conclusions
Representative high-performance liquid chromatograms of all the materials tested at the first 24 hours of immersion in artificial saliva. Chromatographic conditions described in text. BisGMA, bisphenol A-glycidyl dimethacrylate; BPA, bisphenol A; TEGDMA, triethylene glycol dimethacrylate.
Representative high-performance liquid chromatograms of conventional resin composite tested at the end of 7 days and 14 days after immersion in artificial saliva. Chromatographic conditions described in text. BisGMA, bisphenol A-glycidyl dimethacrylate; BPA, bisphenol A; TEGDMA, triethylene glycol dimethacrylate.
Representative high-performance liquid chromatograms of conventional resin composite tested at the end of 30 days and 60 days after immersion in artificial saliva. Chromatographic conditions described in text. BPA, bisphenol A; TEGDMA, triethylene glycol dimethacrylate;UDMA, urethane dimethacrylate; BisGMA, bisphenol A- glycidyl dimethacrylate
Conventional resin composite scanning electron microscope images after A) 7 days and B) 60 days of immersion in artificial saliva. Original magnification 1000×. Energy-dispersive spectroscopy analysis after C) 7 days and D) 60 days.
Contributor Notes
Clinical Relevance
CAD-CAM materials release less monomer than the conventional resin composite and could be considered as the treatment of choice when replacing large amalgam or resin composite restorations.